The protagonists of the series are the three Kisugi sisters—Hitomi, Rui and Ai—who run a café called Cat's Eye. The sisters lead a double life as a trio of highly skilled art thieves, leaving cards with the name "Cat's Eye" at the scene of their crimes. They steal works of art (mostly paintings) that belonged to their long-missing father, Heinz (who was a famous art collector during the Nazi regime), in the hopes of him contacting them. Toshio, the police officer investigating this case is the fiancé of Hitomi. He also swears to capture and bring down the Cat's Eye Gang.

Note: Includes the pilot one-shot and one extra chapter.