The story revolves around the amnesiac girl Ryouko Otonashi, who is a student at Hope's Peak Academy, and the sharp-tongued Ultimate Neurologist Yasuke Matsuda, with whom she is infatuated.

A month after The Tragedy of Hope's Peak Academy, the school is full of unrest and secrets, with many people attempting to find out what truly happened and who is to blame. Despite not wanting any of it, Ryouko is connected to the incident and soon gets caught up in its aftermath, learning more and more about what happened.

(Source: Danganronpa Wiki, edited)